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Steroid Treatment in Bronchopulmonary Dysplasia [Zeynep Kamil Med J]
Zeynep Kamil Med J. 2015; 46(2): 80-83

Steroid Treatment in Bronchopulmonary Dysplasia

Selahattin Akar, Sevilay Topçuoğlu, Güner Karatekin, Fahri Ovalı
Zeynep Kamil Gynecology and Pediatrics Training and Research Hospital, Neonatal Intensive Care Unit, Istanbul

INTRODUCTION: Bronchopulmonary Dysplasia (BPD) is a chronic lung disease of premature newborns treated with positive pressure ventilation and oxygen. In this study we aimed to evaluate the efficiency of steroid usage in BPD patients.
METHODS: Eighteen preterm newborn born between 01.01.2012 and 21.12.2012 were enrolled to the study. The oxygen need before and after
treatment was evaluated.
RESULTS: The mean gestational age of patients were 26.81±1.87 (24-31) weeks, length of hospital stay 77.5±12.92 (23-142) days, length of steroid treatment 7.85±3.43 (3-11 ) days, starting with treatment 39.8±17.11 (14-79) days, mean cumulative dosage of steroid 0.65±0.27 (0.3-1.2) mg/kg, extubation day after treatment 7.82±8.14 (1-28), leaving CPAP after treatment 16.6±14.4 (4-61). At the beginning of the treatment 14 patients were intubated and 4 were in CPAP. After treatment one of the four patients in CPAP stayed in CPAP, one needed oxygen in hood, one in free flow and the other no more oxygen treatment, from 14 intubated patients 5 needed nasal CPAP, one oxygen in hood, one in free flow and the other 7 stated intubated.
DISCUSSION AND CONCLUSION: Although steroids are used in many centers in different therapy schedules, short term effects are still controversial. Since many factors
confine to perform a randomized controlled study on this subject, observational studies are very important to gather more information.

Keywords: bronchopulmonary dysplasia, steroid, chronic lung disease

Selahattin Akar, Sevilay Topçuoğlu, Güner Karatekin, Fahri Ovalı. Steroid Treatment in Bronchopulmonary Dysplasia. Zeynep Kamil Med J. 2015; 46(2): 80-83

Corresponding Author: Selahattin Akar, Türkiye
Manuscript Language: English
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