THE EFFECT OF THICKNESS AND PATTERN OF ENDOMETRIUM ON SUCCESS RATE ON HCG DAY IN INFERTILE COUPLES TREATED WITH OVULATION INDUCTION VIA GONADOTROPINS AND INTRAUTERINE INSEMINATION

INTRODUCTION: Ovulation induction and intrauterine insemination is the first line therapy chosen for infertile couples. In this study, we investigated the effect of endometrial thickness and endometrial pattern; examined on HCG day, on the success rate of OI-IUI performed in unexplained infertility cases on the day of HCG.
METHODS: In this study 101 couples and 132 IUI cycle who were diagnoses unexplained infertility were examined prospectively.
RESULTS: 22 successful pregnancy was achieved in 132 cycles, the rate of pregnancy was calculated as %16.6 per cycle and %21.7 per patient. There was no significant difference between clinically proved pregnancy-positive and negative outcome groups regarding FSH dosage, duration of stimulation, basal FSH level, basal E2, TPMSS, number of IUI cycle, follicle diameter. Infertility period was calculated as 2.1 ± 1.4 years, and 4.1 ± 2.3 years positive and negative outcome groups respectively. The difference was statistically significant (p < 0.05). The number of an antral follicle and follicle count on HCG day was significantly different on pregnancy positive group compared to pregnancy negative group (p< 0.05). Endometrial thickness was measured as 9.8±1.1 mm and 9.6±3.5 mm in groups with positive and negative outcomes respectively. There was no significant difference regarding endometrial thickness and endometrial pattern.
DISCUSSION AND CONCLUSION: There was no significant difference between pregnancy clinically proven and unproven groups in terms of endometrial thickness and endometrial pattern on the day HCG performed.