The Expressions of Luteinizing Hormone and Sex Steroid Hormone Receptors in Human Fallopian Tube During the Menstrual Cycle

INTRODUCTION: Expression of Luteinizing hormone (LH) receptors has been showed in the tuba uterina; but their role in the Fallopian tube is still unknown. During the normal menstrual cycle, female reproductive system is exposed to fluctuating levels of sex
steroids, including estrogen and progesterone. In this study, we present the cyclical variations of tubal LH, estro-gen receptors (ER), and progesterone receptors (PR).
METHODS: Twenty women operated for benign causes were included in this study. Fallopian tubes from the different stages of menstrual
cycle were collected. Then these tubes sections were examined using immunohistochemistry.
RESULTS: Expression of LH receptor did not change according to phases of menstrual cycle and there is no significant difference between follicular phase and luteal phase groups. Ac-cording to the result of statistically analyzed, there is not a significantly differences between the PR of follicular phase and luteal phase.
DISCUSSION AND CONCLUSION: We report on differences in LHR, SHR expression in the Fallopian tube from cases with follicular phase compared with luteal phase. This information may be important for the understanding of normal tubal function.