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Preoperative inflammatory markers in the prediction of adnexal torsion
Mehmet Güçlü1, Ismail Bağlar1, Esra Keles2, Aslıhan Güler11Department of Obstetrics and Gynecology, University of Health Sciences, Kartal Lutfi Kirdar City Hospital, Istanbul, Turkey2Department of Gynecologic Oncology, Health Sciences University, Kartal Lutfi Kirdar City Hospital, Istanbul, Turkey
INTRODUCTION: To investigate the role of preoperative inflammatory markers in the diagnosis of adnexal torsion (AT).
METHODS: A retrospective case-control study was carried out, comparing 110 patients who had undergone surgery for AT with a control group of 102 patients. Demographic characteristics and preoperative hematological parameters were compared between those with and without adnexal torsion.
RESULTS: Patients diagnosed with AT had significantly lower age, gravidity, and parity compared to the control group. The AT group had elevated levels of WBC, neutrophils, platelets, and NLR, and lower levels of MPV. Multivariate analysis revealed that NLR, WBC, and MPV were independently predictive of AT. The NLR cut-off value was determined to be 2.64. Based on this value, the sensitivity, specificity, positive predictive value, and negative predictive value were 84.3%, 78.2%, 78.2%, and 84.3%, respectively.
DISCUSSION AND CONCLUSION: This study suggests that preoperative inflammatory markers, particularly NLR, may be valuable tools for improving the early diagnosis of AT. In addition, NLR demonstrated superior diagnostic accuracy over WBC count.
Manuscript Language: English
