THE ENDOMETRIUM IN PATIENTS WITH METABOLIC SYNDROME

INTRODUCTION: Metabolic disorders can increase the risk of endometrial diseases and endometrial cancer. Patients with metabolic syndrome are at risk for endometrial pathologies. Advising routine gynecological examination even to the patients with metabolic syndrome having no gynecological complaints may be helpful in early diagnosis.
METHODS: 120 patients diagnosed with metabolic syndrome in the Internal Diseases Outpatient Clinic were examined for endometrial diseases in the Gynecology Clinic. Data were analyzed using SPSS 16 statistical software, and Chi-square test was performed. p<0.05 was considered as statistically significant.
RESULTS: 36 patients had undergone a diagnostic curettage. There was no endometrial cancer in any patient. The rate of endometrial hyperplasia without atypia was found significantly increased in the patient group with abnormal uterine bleeding when compared to the patient group with menopause having postmenopausal bleeding and an increased endometrial thickness (p=0.001).
DISCUSSION AND CONCLUSION: Endometrial pathology was diagnosed in 15% of the patients with metabolic syndrome. It was concluded that the question of whether routine gynecological examination of metabolic syndrome patients is required in clinical practice could be answered by further studies including larger patient groups.