Quick Search
Comparison of hemogram parameters in pregnant women with gestational diabetes mellitus and healthy pregnant women
Mehmet Kağıtçı, Nalan Kuruca, Deniz Dereci Delibaş, Şenol ŞentürkDepartment of Obstetrics and Gynecology, Recep Tayyip Erdoğan University Faculty of Medicine, Rize, TurkeyINTRODUCTION: Gestational diabetes mellitus (GDM) is the most common endocrinopathy in pregnant women. The aim of this study is to investigate the relationship between changes in complete blood count parameters, a common and inexpensive test, and GDM.
METHODS: In this retrospective study, changes in the complete blood count parameters of pregnant women who underwent a 75-gram oral glucose tolerance test at 24–28 weeks of gestation between October 2021 and October 2022 were compared with healthy pregnant women.
RESULTS: A total of 424 pregnant women were included in the study. Of these, 107 (25.2%) were in the GDM group, and 317 (74.8%) were in the control group. The levels of white blood cell, neutrophil, red blood cell, hemoglobin, and hematocrit were higher in the GDM group (p=0.015, 0.02, 0.025, 0.01, 0.000). Basophil and mean corpuscular hemoglobin concentration (MCHC) levels were found to be lower in GDM patients (p=0.029, 0.009). Logistic regression analyses showed relationships between age, basophil, MCHC, and hematocrit levels. ROC analyses of the relevant blood parameters showed low sensitivity or specificity.
DISCUSSION AND CONCLUSION: Complete blood count parameters are affected in GDM patients, but clinical use seems challenging. Advanced age is also associated with an increased GDM risk.
Manuscript Language: English
