E-ISSN 2757-8062
Volume: 55 Issue: 1 Year: 2024

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The role of anti-mullerian hormone in determining ovarian reserve in patients with endometrioma and benign cysts [Zeynep Kamil Med J]
Zeynep Kamil Med J. 2024; 55(1): 29-33 | DOI: 10.14744/zkmj.2023.71084

The role of anti-mullerian hormone in determining ovarian reserve in patients with endometrioma and benign cysts

Ergül Demirçivi1, Duygu Vardağlı2, Ali İsmet Tekirdağ3, Özgür Akbayır3, Ahmet Gülkılık3, Beyhan Ömer4, Sezai Sahmay5
1Department of Obstetrics and Gynecology, Istanbul Medeniyet University, Istanbul, Turkey
2Division of Health Service Vocational School, Istanbul Esenyurt University, Istanbul, Turkey
3Department of Obstetrics and Gynecology, Istanbul Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey
4Department of Biochemistry, Istanbul Universitiy Faculty of Medicine, Istanbul, Turkey
5Department of Obstetrics and Gynecology, Istanbul Universitiy Cerrahpasa Faculty of Medicine, Istanbul, Turkey

INTRODUCTION: Our aim was to determine the effects of endometrioma by itself and its surgery on ovarian reserve via pre- and postoperative serial measurements of Anti-Mullerian Hormone (AMH) in patients with endometrioma and benign cysts.
METHODS: Our study was conducted at an education and research hospital as a prospective controlled clinical trial. Participants were divided according to their diagnosis into endometrioma and non-endometrioma groups. Serial blood samples of the patients for serum AMH levels were collected preoperatively, and postoperatively at the first week, first month, and third month, respectively.
RESULTS: A total of 46 patients (25 for the study and 21 for control groups) were included in the study. The mean age of our patients was 31.8±5.57 in the endometrioma group and 29.38±8.64 in the control group. The AMH value was lower in the endometrioma group, but the difference did not reach statistical significance (p>0.05). However, in the postoperative AMH levels measured at the 1st week, 1st month, and 1st year, the values were significantly higher in the non-endometrioma group compared to the endometrioma group (p<0.05).
DISCUSSION AND CONCLUSION: According to our study, we can conclude that endometrioma surgery affects ovarian reserve significantly and more negatively than benign cystectomies.

Keywords: Anti-mullerian hormone (AMH), benign cyst, endometrioma, ovarian reserve, surgery.

Ergül Demirçivi, Duygu Vardağlı, Ali İsmet Tekirdağ, Özgür Akbayır, Ahmet Gülkılık, Beyhan Ömer, Sezai Sahmay. The role of anti-mullerian hormone in determining ovarian reserve in patients with endometrioma and benign cysts. Zeynep Kamil Med J. 2024; 55(1): 29-33

Corresponding Author: Ergül Demirçivi, Türkiye
Manuscript Language: English
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