E-ISSN 2757-8062
Volume: 55 Issue: 3 Year: 2024

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The evaluation of extraintestinal manifestations in children diagnosed with inflammatory bowel disease: A single-center experience [Zeynep Kamil Med J]
Zeynep Kamil Med J. 2023; 54(3): 113-118 | DOI: 10.14744/zkmj.2022.94830

The evaluation of extraintestinal manifestations in children diagnosed with inflammatory bowel disease: A single-center experience

Didem Gülcü Taşkın1, Arzu Gülseren2
1Department of Pediatric Gastroenterology and Hepatology, Adana City Training and Research Hospital, Adana, Türkiye
2Department of Pediatric Gastroenterology and Hepatology, Kayseri City Training and Research Hospital, Kayseri, Türkiye

INTRODUCTION: We aimed to examine the relationship between the disease activity index rates at the time of diagnosis and the development of extraintestinal manifestations (EIMs) in children and adolescents with inflammatory bowel disease (IBD).
METHODS: Our study was conducted with 57 children and adolescent patients diagnosed with IBD between 2018 and 2022. The records of the patients were reviewed retrospectively. For the evaluation of IBD activity, Pediatric Crohn’s Disease Activity İndex and Pediatric Ulcerative Colitis Activity İndex measurements were made.
RESULTS: Fifty-seven patients with a diagnosis of IBD were included in the study. When the activity status of the disease was classified as mild, moderate, and severe, there were 11, 14, and 32 patients, respectively. The most common EIM was arthralgia, and it was shown to occur in 23 (40.4%) patients. The presence of EIM was analyzed in 2 (18.2%) patients in mild disease, in 5 (35.7%) patients in moderate disease, and in 17 (53.1%) patients in severe disease, and there was no significant difference between the groups (p=0.110). The area under curve value was found to be 0.623 in the receiver operating characteristic curve to detect the presence of EIM for ulcerative colitis patients (p=0.242).The ideal cutoff value was determined as 67.5, the sensitivity was calculated as 61.5%, and the specificity was calculated as 42.1%.
DISCUSSION AND CONCLUSION: It was found that the presence of EIM at the time of diagnosis was more common in the presence of severe disease, but the result was not significant.

Keywords: Extraintestinal manifestations, inflammatory bowel disease, Crohn’s disease, ulcerative colitis.

Corresponding Author: Arzu Gülseren, Türkiye
Manuscript Language: English
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