INTRODUCTION: The aim of this study is to assess the impact of pre and intra cycle spermiogram parameters on treatment outcome in IUI cycles of couples with optimal female cycle characteristics.
METHODS: The study group comprised of infertile couples diagnosed as anovulation, grade 1-2 endometriosis, unexplained or male factor infertility. Women included in this study underwent ovulation induction and women with optimal cycle characteristics were included in the analysis to figure out the individual impact of sperm parameters on cycle outcome in terms of clinical pregnancy.
RESULTS: Precycle sperm concentration, semen volume, duration of abstinence, total progressive sperm counts, pre and intra cycle progressive motile sperm concentrations were significant predictors for clinical pregnancy. Additionally, parameters of abstinence and total progressive motile sperm count evaluated on IUI day were found to significantly predict favorable outcome. Multivariate regression analysis was conducted to show adjusted associations and analysis revealed that intracycle duration of abstinence and precycle total progressive motile sperm counts were significantly associated with clinical pregnancy.
DISCUSSION AND CONCLUSION: It is showed that intracycle duration of abstinence and precycle total progressive motile sperm counts were significant predictors for IUI cycles with optimal female partner reproductive properties.