INTRODUCTION: This study aims to evaluate ocular surface symptoms and their association with platelet-to-lymphocyte ratio (PLR) in patients who were clinically confirmed with coronavirus disease 2019 (COVID-19) using Ocular Surface Disease Index (OSDI) questionnaire.
METHODS: Thirty-five COVID-19 hospitalized patients were included in the study. All patients had positive severe acute respiratory syndrome coronavirus 2 reverse-transcription polymerase chain reaction test results of nasopharyngeal and throat swab specimens as well as positive findings on computed tomography consistent with COVID-19. Ocular and medical histories were obtained from patients. Laboratory findings were noted. OSDI questionnaire was used to evaluate ocular surface symptoms.
RESULTS: There were 20 females (57.1%) and 15 males (42.9%) with a mean age 40.5 (95% CI: 35.845.2) years in the study. The mean OSDI scores were 12.6 (95% CI: 7.817.5). OSDI scores were significantly correlated with PLR (r=−0.516, p=0.028).
DISCUSSION AND CONCLUSION: Ocular surface problem is likely to occur in COVID-19 patients even in the absence of apparent ocular surface findings. PLR may have a relevance to ocular surface symptoms in COVID-19 patients.