Relationship between umbilical artery Doppler indices and adverse pregnancy outcomes in women with insulin-dependent diabetes mellitus

INTRODUCTION: It is intended to research the value of umbilical artery (UA) and middle cerebral artery (MCA) Doppler indices in predicting adverse pregnancy outcomes in women with insulin-dependent diabetes mellitus.
METHODS: The study was planned at Zeynep Kamil Women and Chil-dren’s Diseases Training and Research Hospital. Pregnant women were divided into two groups: group 1 consisted of 123 fetuses with normal pregnancy outcomes and group 2 had 74 fetuses with adverse pregnancy outcomes. The value of the UA sys-tole/diastole (S/D) ratio was questioned to predict possible adverse pregnancy outcomes. Differences in Doppler measurements between the groups with p<0.05 were considered statistically significant.
RESULTS: UA S/D ratios were established as ultrasonographical parameters in predicting normal pregnancy outcomes at 28th, 32nd, and 36th weeks of gestation, with cutoff values of 2.58, 2.56, and 2.62, respectively. Negative predictive values of these three cutoffs for adverse pregnancy outcomes were 70.21%, 72.53%, and 69.03%, respectively.
DISCUSSION AND CONCLUSION: UA S/D ratios may be helpful to the clinic as ultrasonographical measurements to predict the normal pregnancy outcomes at 28th, 32nd, and 36th weeks of gestation.